SERIZE SYSTEMS BIOS v3.05
Copyright (C) 2010-2026 Arturo Serize, MPH, PA-C
All clinical workflows reserved.
serize@dev:~$ _
$ whoami

Arturo Serize MPH, PA-C

15 years at the bedside. I got tired of broken workflows, so I started building the tools that should already exist.

$ cat /etc/motd
Clinical systems builder · Healthcare UX · Workflow engineer · Published clinical researcher

$ cat about.md

From Clinical Frustration to Technical Innovation

I've spent over a decade in neonatology and infectious disease medicine. In every single setting, every single unit, the same pattern repeats: clinicians working against their own tools every single shift.

Every system I build comes from a real problem I've lived. I don't design from a spec sheet — I design from the bedside, where a bad interface costs minutes you don't have.

My approach: identify the broken workflow, design the fix, build a working prototype, and prove it works. No committee. No 18-month sprint. Just solutions.

15+
Years Clinical
14+
Systems Built
12
Publications
0
Critical Deviations

$ ls -la ./projects/

Healthcare Solutions

FLAGSHIP

A.T.L.A.S. Adaptive Trial Logistics & Assessment System

Active Development

Modular clinical trial operations suite built as single-file HTML applications. No server, no database, no PHI, no IT department required. Each module is a self-contained .html file — open it in a browser and it works.

Enrollment & Screening

  • SHERLO — Screening & History Eligibility Review Log
  • HIET — NICHD Modified Sarnat Examination Tool

Operations

  • GATE — Gated Assessment & Trial Eligibility
  • CHART — Clinical Activity Resource Tracker
  • VISTA — Visit Interval Scheduling & Timeline Advisor
  • DRIFT — Deviation Recording & Follow-up Tracker
  • KITS — Kit Inventory Tracking System
  • B.I.O. Buddy — Biospecimen Input & Output

Compliance & Team

  • PREP — Protocol Readiness & Execution Planner
  • ROLES — Research Operations Lineup & Expertise System
  • WATSON — Workflow Assistance Tool for Study Operations
  • Portal — Sponsor Monitoring Dashboard

KEY:"Sneakerware" — walk it in on a thumb drive. No IT integration, no network access, no institutional approval. Zero dependencies. Zero PHI. Just open the file.

Vanilla JavaScriptSingle-File ArchitecturelocalStorageZero DependenciesCSV Export

PRISM Pipeline for Real-time Infection Signal Mining

Active Development

Multi-API biomarker intelligence platform. Pulls from PubMed, ClinicalTrials.gov, UniProt, KEGG, and STRING, then runs Bayesian probability analysis with composite ROC curve generation. Embeds a full R runtime in the browser via WebR.

KEY:Bayesian diagnostic probability engine with real-time API integration and embedded R statistical computing — all client-side, zero backend.

WebRBayesian AnalysisROC CurvesREST APIsPubMedd-prime

NEC Tool Perez-Serize NEC Predictive Tool

Research / Validation
NEC Tool interface

Dual-component clinical prediction engine for necrotizing enterocolitis. Monitors 9 biomarkers (ANC, WBC, platelets, CRP, fecal calprotectin, pH, lactate, base deficit, eosinophils), scoring both absolute abnormality and temporal trajectory to detect NEC 24-48 hours before clinical deterioration. Evidence-based thresholds from published literature with clinical pattern bonuses for multi-system co-occurring abnormalities. 5,900+ lines with animated demo walkthrough, algorithm explainer, and validation dashboard.

KEY:No single biomarker diagnoses NEC. This tool combines 9 markers across time — trajectory analysis that creates a synergistic risk assessment where three high-priority markers dropping simultaneously is more predictive than any marker alone.

Predictive AnalyticsTemporal Trajectory Analysis9-Biomarker EngineChart.jsEvidence-Based ThresholdsClinical Validation

NICSTEM NICU-Centric EHR Interface

Functional Prototype
NICSTEM interface

Redesigned electronic health record interface. Replaced complex menu navigation with an intuitive visual approach using anatomical diagrams and drag-and-drop charting. Runs on top of existing EHR backends without vendor lock-in. 4,700+ lines.

KEY:Matches interface design to natural clinical thought patterns, dramatically reducing documentation time.

ReactReal-time DataClinical Workflow OptimizationFHIR Integration

N.A.N.O. Nanopore Assay for Neonatal Organism Detection

Research / Validation
N.A.N.O. interface

Prospective concordance study comparing Oxford Nanopore MinION metagenomic sequencing to standard PCR and viral culture for rapid neonatal HSV detection. Full clinical protocol with custom 1,300+ line tracking dashboard: enrollment management, specimen workflow, sequencing QC metrics, turnaround time analytics, and concordance reporting.

KEY:Clinician-designed translational research — wrote the science AND built the operational tooling. From clinical question to protocol to dashboard, end to end.

Nanopore SequencingTranslational ResearchClinical ProtocolStudy DashboardMetagenomics

B.U.G. MYCIN-Style Neonatal Sepsis Advisor

Functional Prototype
B.U.G. interface

Clinical decision support tool inspired by the original MYCIN expert system. Guides clinicians through neonatal sepsis evaluation using rule-based reasoning, incorporating patient-specific factors to generate antibiotic recommendations with transparent confidence scoring.

KEY:Brings the rigor of expert system reasoning to bedside sepsis decisions, making the clinical logic visible and auditable.

ReactExpert SystemsClinical Decision SupportNeonatal ID

H.A.L. Heuristic Antimicrobial Logic

Active Development
H.A.L. interface

Antimicrobial stewardship engine with a retro terminal aesthetic. Evidence-based antimicrobial selection guidance, dosing calculations, and spectrum analysis to support institutional stewardship programs.

KEY:Encodes institutional antibiogram data and stewardship protocols into an interactive decision engine that clinicians actually want to use.

JavaScriptAntimicrobial StewardshipClinical AlgorithmsRetro CRT Interface

NICSPORT Neonatal Transport Documentation System

Functional Prototype
NICSPORT interface

Mobile documentation platform for high-pressure transport. Offline persistence, smart exam toggles, vitals reminders, digital consent. 3,200+ lines. Designed by someone who's actually been in the back of a transport unit at 3 AM.

KEY:First transport documentation system designed by a clinician who does the transports.

Offline-First PWAJavaScriptlocalStoragePDF Generation

S.A.G.E. System for Algorithmic Generation of Evaluations

Functional Prototype
S.A.G.E. interface

Visual monitoring system that transforms complex vital signs into intuitive patterns using a retro-style interface. Converts traditional measurements into dynamic visual displays that make patient status immediately clear.

KEY:Makes complex vital sign patterns immediately recognizable through intuitive visual displays.

JavaScript CanvasReal-time VisualizationPattern RecognitionRetro Gaming UI

B.L.O.O.M. BPD Lung Optimization & Outcome Monitor

Functional Prototype
B.L.O.O.M. interface

Comprehensive BPD weaning monitor that tracks ventilator parameters, calculates composite lung health scores, and visualizes trends over time. CRT-aesthetic dashboard with real-time scoring breakdown across oxygen burden, pressure support, and weaning trajectory.

KEY:Converts subjective 'how is the baby doing on the vent' into a quantifiable, trackable BLOOM score with transparent component weighting.

JavaScriptCanvasCRT InterfaceRespiratory MedicineBPD PreventionReal-time Monitoring

R.E.F.L.U.X. Reflux Evidence Framework: Longitudinal Unit Exploration

Research / Validation
R.E.F.L.U.X. interface

Standardized bedside GERD assessment tool for neonatal patients. Structured observation protocol with assessment history, trend tracking, unit-level dashboards, and printable source documents. Built for a pilot study standardizing neonatal reflux evaluation.

KEY:Replaces subjective 'the baby looks refluxy' with systematic, trackable bedside assessment data.

JavaScriptClinical AssessmentNeonatal GIPilot StudyData Export

O.R.O. Oxygen Retinopathy Optimizer

Functional Prototype
O.R.O. interface

Oxygen management tool to minimize ROP risk in neonatal patients. Tracks SpO2 targets, FiO2 adjustments, and exposure windows to maintain optimal oxygenation while reducing cumulative oxidative stress.

KEY:Turns the complex relationship between oxygen exposure and ROP risk into actionable, real-time clinical guidance.

JavaScriptNeonatal OxygenationROP PreventionReal-time Monitoring

M.I.N.D. Multi-domain Integrated Neurocognitive Diagnostic

Functional Prototype
M.I.N.D. interface

Rapid dementia classification tool that integrates multiple cognitive assessment domains into a unified diagnostic workflow. Structured scoring and automated severity grading.

KEY:Consolidates fragmented neurocognitive assessments into a single, systematic diagnostic pathway.

Vanilla JavaScriptNeurocognitive AssessmentDiagnostic Classification

NICUFlex NICU Staffing Optimizer

Functional Prototype
NICUFlex interface

Multi-site staffing allocation tool. Census-driven workload calculation with automated APP assignment recommendations across hospital sites. Color-coded acuity, real-time status tracking.

KEY:Operational workflow optimization — resource allocation meets clinical staffing intelligence.

JavaScriptOperationsWorkforce ManagementMobile-First

$ cat /proc/stack

Technology Stack

Clinical Systems

  • Epic & Cerner
  • REDCap Administration
  • EDC Platforms (Rave, Medrio)
  • HL7 / FHIR Standards

Data & Analytics

  • SQL & Clinical Databases
  • R Statistical Analysis
  • Python
  • Clinical Trial Analytics

Development

  • JavaScript / React
  • Offline-First Architecture
  • Responsive Design
  • API Integration

Environment

  • Linux (daily driver)
  • Git / CLI-first workflow
  • cool-retro-term
  • Vim / VS Code

$ cat philosophy.md

Development Approach

Clinical First

Every feature starts with understanding the clinical need, not the technical possibility.

Rapid Iteration

Build, test with actual clinicians, refine. No solution survives first contact with a busy unit.

Bulletproof

If it doesn't work at 3 AM with stressed staff, it doesn't work.

Zero Friction

No servers. No logins. No IT approval. Open the file and it works.

$ ./contact.sh

Let's Build Something Better

I bridge clinical and technical teams. Whether you need someone who understands both the workflow and the code, let's talk.

English & Spanish (native) · Portuguese (fluent)